To Evaluate The Efficacy Of Panchavalkala Kashaya In The Management Of Mild To Moderate Infected Wound

objective:-

To Assess the Efficacy of Panchavalakala Kashaya in management of mild to moderate infected wound.

Plan of Study-

Total 40 Patients of vrana will be registered from OPD/IPD of Department of Shalya Tantra, S.S.H., B.H.U., Varanasi. Patients will be registered urespective of their age, sex and religion which are fulfilling the inclusion and exclusion criteria.

Patients will be enrolled after thorough interrogation, laboratory investigations and clinical assessment on a set proforma.

Effect of Panchavalkala kwatha is compared with normal saline. Clinical study will be conducted on patients with infected wound by randomly dividing them into 2 groups :-

A)  0.9% Normal Saline (Control Group)

B)   Panchavalkala Kwatha (Trial Group)

**Lab.**Investigations:

Hb%

Total and differential WBC count with ESR

Serum creatinine/ Blood urea

Blood sugar

RFT/LFT

Wound microbial load count (Asses for bactarial load range between mild to moderate)

Wound tisue biopsy-HPE ( 0 day and 28th  day)

HIV

·      Hbs Ag

Assessment criteria-:

Subjective -:

Physical Examination of the wound:

Objective -:

Microbiological  study- (Assess for bacterial load range between mild to                    moderate)

Histopathological examination

(Registration day - 0 day After    - 28th day)

Biochemical Parameter-:

To Assess Quantitative Estimation of VEGF, before treatment (0 day), during treatment (14 and 28 day).