跳至主要内容
临床试验/NCT06189911
NCT06189911已完成不适用

The Risk Factors for Perioperative Blood Transfusion in Open Liver Resection, a Retrospective Cohort Study Development of a Transfusion Scoring System to Predict the Requirement for Perioperative Blood Transfusion in Open Liver Resection

Chiang Mai University0 个研究点目标入组 1,201 人开始时间: 2006年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,201
主要终点
the pre-operative risk factors of perioperative packed red cell transfusions in open liver resection procedures.

研究概览

简要总结

This observational study is specifically designed to identify the pre-operative risk factors that significantly contribute to perioperative packed red cell transfusions in open liver resection procedures.

The main question it aims to answer are:

  1. What are the risk factors of peri-operative blood transfusion in open liver resection procedures
  2. What are the difference outcomes between patients who receive blood transfusion and the other group.

Researcher will compare perioperative factor and post operative outcomes between transfused and non-transfused group

详细描述

After approval of the study protocol from the institutional review board of Chiangmai University (Approval number: ANE-2564-08020), we performed a retrospective review of all patients who underwent an elective open liver resection in our specialized hepato-biliary center from January 2006 through December 2017. This retrospective inquiry comprised 808 patients.

The data was systematically retrieved from electronic medical records. Baseline characteristics including age, gender, body mass index (BMI), co-morbidity, American Society of Anesthesiologists (ASA) classification, diagnosis, hepatitis profile, Child-Pugh classification, cirrhosis, the largest tumor size, previous liver resection, and pre-operative laboratory investigations were collected.

The following intra-operative data were collected: type of liver resection, hilar resection, vascular reconstruction, volume and type of fluid administration, estimated blood loss, packed red cell and blood product transfusion, and operation time. The definitions of liver resection and the type of hepatectomy were aligned with the anatomic classification of the Brisbane 2000 Terminology

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All genders age above 18 year old who underwent open liver resection from 2006-2017
  • Elective open liver resection

排除标准

  • Patients who death during the course of a surgical operation

结局指标

主要结局

the pre-operative risk factors of perioperative packed red cell transfusions in open liver resection procedures.

时间窗: the transfusion of packed red cells during the operation and 48 hours after surgery

Significant risk factors for perioperative blood transfusion were determined by factors with a p-value \< 0.05 derived from the multivariable logistic regression analysis. This analysis facilitated adjustments for potential confounders to identify the independent risk factors associated with perioperative blood transfusion

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Warangkana Lapisatepun

Assistant professor

Chiang Mai University

相似试验

Perioperative Blood Transfusion in Open Liver... | 临床试验