Assessment of Left Atrial Mechanical Function With a True 3D Ultrasound Array and Comparison With the Transthoracic and Transesophageal Echocardiography: A Single Center Interventional Study in Patients Scheduled for Ablation Procedure
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- changes in left atrial appendage flow
研究概览
简要总结
Chronic atrial fibrillation is a challenging arrhythmia requiring additional radiofrequency ablation besides pulmonary vein isolation. Atrial contractility in these patients is often impaired. Until now mapping catheters were used on virtual geometry maps of left atrium. However, changes in atrial volume cannot be assessed with these systems Assessments of atrial volumes with echocardiography relies on 2D and 3D measurements and modeling. The AcQMapTM 3D High Resolution Imaging and Mapping System (AcQMap) has a unique 3D array of ultrasound crystals, which can measure true 3D dimensions of the heart chamber. For the first time, true atrial volumes can be measured. Changing from atrial fibrillation to sinus rhythm causes changes in atrial volume and might be associated with quantitative systolic and diastolic function of the left ventricle measured with the Transesophageal Echocardiography.
详细描述
Comparison of true 3D atrial volume changes to TEE and TTE findings as well as atrial pressure curves during left heart catheterization. Changing from atrial fibrillation to sinus rhythm causes changes in atrial volume and might be associated with quantitative systolic and diastolic function of the left ventricle measured with the Transesophageal Echocardiography
Measurement of true left atrial ejection fraction and comparison to 2D echocardiographic parameters such as transesophageal measured flow velocity of the mitral inflow tract, pulmonary vein flow, the left atrial appendage flow
Inclusion:
Patients undergoing electrophysiological study with the AcQmap System Age ≥18 years and signed informed consent German speaking
Exclusion:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing electrophysiological study with the AcQmap System
- •Age ≥18 years and signed informed consent
- •German speaking
排除标准
- •Mechanical mitral valve
- •Contraindication for left atrial ablation procedure such as: Intra-cardiac clot,
- •Pregnancy
研究组 & 干预措施
transesophageal echocardiography
Comparison of 3D Ultrasound with transesophageal echokardiography
干预措施: transesophageal investigation (Device)
结局指标
主要结局
changes in left atrial appendage flow
时间窗: 1 hour
Changes in Mitral flow velocity
时间窗: 1 hour
changes in pulmonary vein flow
时间窗: 1 hour
次要结局
未报告次要终点
研究者
Werner Baulig
PD Dr. med. Werner Baulig, Senior consultant
Klinik Hirslanden, Zurich
