NCT01092793已完成不适用
Effect of Superba Krill on Inflammation in Patients With Coronary Artery Disease
Oslo University Hospital2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2010年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Inflammatory blood status
研究概览
简要总结
Atherosclerotic coronary heart disease is a condition thought to involve low-grade inflammation. Several reports, clinical and epidemiological, have demonstrated that intake of fish oil may be beneficial in attenuating the inflammatory process. Still, however, there are lacking data in respect to whether differences in composition of various marine oils may influence the inflammatory status differently.
The hypothesis of the current study is that extract from the antarctic krill (Euphausia superba) is better than traditional fish oils when compared head-to-head with balanced composition of omega 3 content on inflammatory status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 18-80 years
- •Sex: Male and female
- •Stable atherosclerotic coronary heart disease (heart attack >3 months ago or objectified angina pectoris).
- •No hospitalization for heart disease last 3 months.
排除标准
- •Unstable heart disease.
- •Heart failure NYHA class III and IV.
- •Previous valve and/or aortic surgery
- •Significant concomitant disease (i.e. diseases with known inflammatory activation - e.g. various autoimmune diseases, chronic infections, significant acute infections three weeks before or during the study, connective tissue disease, arthritis, chronic pulmonary disease or serious liver- or kidney-disease).
- •Simultaneous involvement in other clinical studies involving intervention.
- •Planned operation or other invasive procedures (e.g. PCI etc.) during the study period.
结局指标
主要结局
Inflammatory blood status
时间窗: 8 weeks intervention
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
已完成
2 期
Inflammatory Pathogenesis of Coronary Atherosclerosis in HIVHuman Immunodeficiency VirusCoronary Artery DiseaseNCT02624180Johns Hopkins University81
已完成
不适用
Effects of Krill Oil on Endothelial Function in Patients With Type 2 Diabetes MellitusType II Diabetes MellitusNCT02091193Danbury Hospital47
已完成
不适用
Inflammation and coronary microvascular dysfunction in middle-aged women, a pilot studyNL-OMON43529cardiologie
已完成
不适用
The Effect of Seaweed Derived Polyphenols on Inflammation and Oxidative Stress in Vivo - The SWAFAX StudyCardiovascular DiseaseNCT02295878University of Ulster80
已完成
2 期
Inflammation and Vascular Function in AtherosclerosisAtherosclerosisNCT00760019Brigham and Women's Hospital58