Memory and Emotion in Acute and Chronic Phases of Cerebrovascular Accident
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 76
- 试验地点
- 2
- 主要终点
- State of anxiety evaluated with STAI-YA scale
研究概览
简要总结
The purpose is to determine the relationship between anxiety and cognitive performances in patients with acute and chronic phases of cerebrovascular accident (CVA). Data from neuropsychological assessment concerning cognitive processes (working and episodic memory) sensitive to different dimensions of anxiety will be analyzed.
The secondary purpose is to evaluate how some neurological (hemispherical lateralization of lesions), psychological (depression) and demographic (quality of life) variables can increase the effects of different dimensions of anxiety on cognitive processes, during the acute and/or chronic phase of CVA.
详细描述
Data will be collected during usual neuropsychological evaluation and cerebral imagery examination (NIHSS, Rankin scale) of patients in acute (0-1 month) and chronic (6 months) phases of CVA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute phase of carotid, vertebrobasilar or lacunar cerebrovascular accident with ischemic or hemorrhagic origin
- •Right-handed
- •Possible cooperation: understanding of French instructions
- •Normal or corrected vision
- •Normal or corrected hearing
- •Mini-mental state examination score higher than pathologic threshold according to age and sociocultural level of patient
- •Possible follow up of patient
排除标准
- •Hearing problems
- •Vision problems
- •Right hemiplegia or acute monoparesis of right upper limb
- •Hemispatial neglect
- •Psychiatric or neurological history possibly interfering with neuropsychological evaluation
- •Important defect of working memory or executive functions
结局指标
主要结局
State of anxiety evaluated with STAI-YA scale
时间窗: 6 months (from CVA)
Apprehension anxiety evaluated with Penn State Worry Questionnaire
时间窗: 6 months (from CVA)
Evaluation of working memory inhibition with Stimulus-response compatibility task
时间窗: 6 months (from CVA)
Evaluation of working memory updating with N-back verbal and visuospatial task
时间窗: 6 months (from CVA)
Evaluation of working memory flexibility with Switching task
时间窗: 6 months (from CVA)
Evaluation of verbal working memory with Wechsler memory scale
时间窗: 6 months (from CVA)
Evaluation of visual episodic memory with Rey and Taylor figure test
时间窗: 6 months (from CVA)
Anxiety proneness evaluated with STAI-YB scale
时间窗: 6 months (from CVA)
Evaluation of visuospatial working memory with Wechsler memory scale
时间窗: 6 months (from CVA)
Evaluation of verbal episodic memory with RL/RI 16 item test
时间窗: 6 months (from CVA)
次要结局
- Depression state evaluated with Back depression inventory(6 months (from CVA))
- Hemispheric lateralization of lesions detected with MRI(up to 1 month from CVA)
- Quality of life evaluated with SF-36 test(after 6 months from CVA)