Cycling Intervention on Symptoms of Patients With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Knee Abduction Moment - Cycling
研究概览
简要总结
This study is designed to determine the effect of a cycling training program which modulates frontal and sagittal plane knee joint loading with graded increases of Q-Factor and cycling workrate in persons with symptomatic knee osteoarthritis.
详细描述
The knee joint is one of the most common joints affected by osteoarthritis, and knee osteoarthritis is primarily observed in the medial compartment. This is in part attributable to the increased load experienced by the medial compartment during level walking. Patients with symptomatic knee osteoarthritis exhibit altered gait mechanics; namely a reduced loading response knee extension moment and an increased internal knee abduction moment. As a surrogate measure for medial compartment joint loading, loading response knee abduction moment in level walking has been shown to increase with the severity of knee osteoarthritis.
Recent gait modification research has shown that increased step-width decreases peak Knee abduction moment for persons with knee osteoarthritis. The inter-pedal width of a bicycle or cycle ergometer, known as Q-Factor, is analogous in cycling to step-width in gait. In contrast to gait, increased Q-Factor has been shown to increase the knee abduction moment during stationary cycling. Modulating sagittal and frontal plane loading of the knee in a graded manner during cycling may promote healthy adaptation to muscle weakness and pain. This adaptation may be manifest through restoration of altered knee joint biomechanics (knee extension moment, knee abduction moment), which, in turn, may also provide benefit to gait mechanics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and Women between the ages of 50 and 75 years old.
- •Diagnosed with medial compartment tibiofemoral osteoarthritis in one of their knees.
- •Be able to walk unaided for at least 25 consecutive minutes.
- •Present with knee pain for at least 6 months occurring on a majority of the days in the month, or on most days (more than or equal to 4 of 7 days in a week) in one or both knees for at least 4 months.
- •Osteophytes on knee x-rays.
- •Grade 2 or higher out of a maximum of 4 on a modified Kellgren/Lawrence grade on the knee radiograph.
排除标准
- •Initial Visual Analog Scale pain scores greater than
- •Diagnosed osteoarthritis of ankles, hips, or symptomatic osteoarthritis of the spine.
- •Arthroplasty of any other lower extremity joint.
- •BMI value greater than 40 kg/m
- •Any major lower extremity injury in the past 6 months.
- •Systemic Inflammatory Arthritis.
- •Systemic Pain Conditions.
- •Neurological Conditions that impact gait or cycling.
- •Pregnant or Nursing Women.
- •Major cardiovascular disease with an exercise limitation prescribed by a physician.
- •Steroid injection at the knee within the previous 3 months.
结局指标
主要结局
Knee Abduction Moment - Cycling
时间窗: Baseline, 1 month, 2 month
Change in Knee Extension Moment during cycling.
Knee Abduction Moment - Gait
时间窗: Baseline, 1 month, 2 month
Change in Knee Extension Moment during gait.
次要结局
- Knee Injury and Osteoarthritis Outcome Score(Baseline, 1 month, 2 month)
- Knee Extension Moment - Gait(Baseline, 1 month, 2 month)
- Visual Analog Pain(Immediately following exercise (walking and cycling).)
- Knee Extension Moment - Cycling(Baseline, 1 month, 2 month)
研究者
Tanner Thorsen
Graduate Research Assistant
The University of Tennessee, Knoxville