Different Low Level Laser Protocols for Therapy of Hyposalivation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Difference in average salivary flow rate, before and after low level laser treatment
研究概览
简要总结
The aim of this study was to compare the effects of different wave lengths of LLLT on salivation in participants suffering from hyposalivation.
This study included 30 participants whose major salivary glands were treated with low intensity diode laser BTL2000 (Medical Technologies, s.r.o., Czech Republic) during 10 consecutive days. Patients were randomly assigned in two groups, each of 15 patients, and treated with LLLT of 830 nm and LLLT of 685 nm, respectively. The whole unstimulated and stimulated saliva was measured each day during 10 days, before and after laser treatment and 10th day after treatment was ended.
详细描述
Low level laser treatment has proved to be effective for a wide range of oral pathologies including oral dryness, but the literature still lacks reports of clinical trials and protocols. The aim of this study was to evaluate the effects of two different laser wave lengths on salivation of patients suffering from hyposalivation. This with purpose to possibly find the optimum laser wavelength for the treatment, and to determine the better protocol for the patients suffering from hyposalivation. This study included 30 patients whose major salivary glands were treated with low intensity diode laser BTL2000 (Medical Technologies, s.r.o., Czech Republic) during 10 consecutive days. Patients were randomly assigned in two groups, each of 15 patients, and treated with LLLT of 830 nm and LLLT of 685 nm, respectively. The whole unstimulated and stimulated saliva was measured in graduated tubes each day during 10 days, before and after laser treatment and 10th day after treatment was ended.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 52 Years 至 85 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •patients suffering from hyposalivation, with medical histories free of radiotherapy and Sjögren's syndrome
排除标准
- •medical histories of radiotherapy and Sjögren's syndrome
结局指标
主要结局
Difference in average salivary flow rate, before and after low level laser treatment
时间窗: 10 days
The whole unstimulated and stimulated saliva was measured each day during 10 days, before and after laser treatment
次要结局
- Average salivary flow rate(1 day (Average salivary flow rate 10th day after the end of LLLT))
研究者
Božana Lončar Brzak
Assisstant Professor
University of Zagreb