NCT00421278已完成2 期
A Clinical Study to Evaluate the Efficacy and Safety of MK0633 in Patients With Atherosclerosis
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 180
- 主要终点
- To evaluate the effects of the drug, MK 0633, on an inflammatory marker in your blood that may affect the plaque in the arteries, know as atherosclerosis
研究概览
简要总结
A study to test the effects of study drug (MK 0633) on patients with Atherosclerotic disease
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 85 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patients with plaque in coronary or leg arteries, known as atherosclerosis or peripheral vascular disease
- •Inflammatory marker found in your blood, known as hsCRP > 0.5 mg/L
排除标准
- •Age < 40 or > 85
- •Heart attack, coronary artery bypass, stroke or unstable angina in last 3 months
- •Liver diseased or abnormalities
- •HIV infection
- •Lupus, rheumatoid arthritis, cancer <5 years
研究组 & 干预措施
1
Experimental
Arm 1: Drug
干预措施: MK0633 (Drug)
结局指标
主要结局
To evaluate the effects of the drug, MK 0633, on an inflammatory marker in your blood that may affect the plaque in the arteries, know as atherosclerosis
时间窗: 4 Weeks
次要结局
未报告次要终点
研究者
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