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临床试验/NCT05584839
NCT05584839招募中不适用

A Comprehensive Statistical Analysis for the Diagnosis of Carpal Tunnel Syndrome

İSMAİL CEYLAN1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
40
试验地点
1
主要终点
Hand Grip Strength

研究概览

简要总结

Trap neuropathies; They are compression neuropathies that occur as a result of peripheral nerves being compressed for various reasons along their anatomical paths. Although each nerve has areas suitable for anatomical entrapment, compression can occur at any point along the nerve. Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by compression of the median nerve at the wrist level. Its prevalence in the general population is 2.5-11%.

Although the majority of cases are idiopathic, it may also occur secondary to pathologies such as pregnancy, diabetes mellitus, thyroid dysfunction, arthritis, wrist fractures and acromegaly or occupation. The diagnosis of CTS is made clinically, but the best method for definitive diagnosis is electrophysiological examination.

Some anthropometric measurements that may be associated with CTS were made and their effect on the risk of CTS was investigated. In a study conducted by Sabry et al. in 2009, it was reported that there may be a relationship between BMI, wrist ratio (ratio of wrist depth to width) and wrist-palm ratio (ratio of wrist depth to palm length) and CTS risk. In a study by Lim et al. in 2008, it was reported that the critical value for wrist ratio was 0.70 and above. However, there were no studies reporting how many percent predictors of anthropometric measurements according to the severity of CTS.

详细描述

The study was planned as a quantitative research. Socio-demographic information form, anthropometric measurements of hand grip strength, palm length, hand width length, wrist circumference length, Visual Analog Scale scale, EMG findings will be evaluated by hand dynamometer.

Trybus et al. Considering the study they conducted in patients with CTS in which they examined hand anthropometric measurements in CTS, it was planned to include 100 patients in the study with a power range of 80% and an effect width of 0.05.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

性别
All
接受健康志愿者

入选标准

  • Admitted to outpatient clinics with symptoms of CTS
  • Findings of CTS in physical examination
  • CTS diagnosis was confirmed by nerve conduction study
  • KTS grade mild or moderate
  • He has not received physical therapy for this reason in the previous 1 year
  • No steroid injection and no treatment for neuropathic pain (pregabalin, gabapentin, etc.)

排除标准

  • - Those under the age of 18 Those with a history of previous surgery or fracture of the affected hand and wrist Those with diabetes mellitus, chronic kidney failure, gout, rheumatoid arthritis, thyroid diseases
  • Pregnant Those with polyneuropathy, radiculopathy, plexopathy, thoracic outlet syndrome

结局指标

主要结局

Hand Grip Strength

时间窗: 0-1 days

The grip strength of the dominant hand is measured using a standard adjustable digital grip dynamometer (Baseline Digital Smedley Hand Dynamometer). Handgrip strength is measured as follows: (a) Each subject is tested while sitting comfortably in a chair without armrests, with their back against the chair; (b) Each subject is instructed to sit with hips and knees flexed 90°, shoulders adducted and neutrally rotated, elbows flexed 90°, forearm rotation 0°, wrists dorsiflexed 0° to 30°, and ulnar deviation 0° to 15°; and asked to squeeze the dynamometer.

次要结局

  • Hand length(0-1 days)

研究者

申办方类型
Other
责任方
Sponsor Investigator
主要研究者

İSMAİL CEYLAN

Head of hand therapy clinic. PhD.

Ahi Evran University Education and Research Hospital

研究点 (1)

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