The Effectiveness of BRAND'S® Essence of Chicken in the Promotion of Resilience and Resistance to Stress-associated Cognitive Inhibition
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Change from baseline in cognitive function at week 2 and week 4
研究概览
简要总结
The purpose of this study is to determine whether BRAND'S® Essence of Chicken are effective in the promotion of resilience and resistance to stress-associated cognitive inhibition.
详细描述
This is a placebo-controlled, randomized, double-blind trial. There will be 100 subjects. Subjects are randomly assigned into either placebo or BRAND'S® Essence of Chicken (BEC), 70cc daily for 2 weeks, group.
Stress test, cognitive function assessment and blood tests will be carried out at Week 0, Week 2, and Week 4 (2 weeks after termination of supplementation).
The primary end-point is the better improvement of cognitive function after supplement with BEC than placebo. The second endpoints include improvement of global health survey and changes of biomarkers related to stress and immunity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged over 20 years,
- •mildly stressed with Perceive Stress Scale (PSS) score higher than 25
- •All the participants should not require medication for their mood disturbance affected by stress during the trial.
排除标准
- •history of chronic diseases
- •any psychiatric or neurological diseases (e.g. depression)
- •other medical illnesses (e.g. stroke, diabetes, other cardiovascular diseases)
- •allergy history to chicken
研究组 & 干预措施
placebo
placebo with the same color, order, taste as BRAND'S® Essence of Chicken , 70cc daily for 2weeks
干预措施: Chicken Essence (Dietary Supplement)
Chicken Essence
BRAND'S® Chicken Essence 70cc, daily for 2 weeks
干预措施: Chicken Essence (Dietary Supplement)
结局指标
主要结局
Change from baseline in cognitive function at week 2 and week 4
时间窗: baseline, week 2, week 4
Working memory, Episodic memory, Attention
次要结局
- Change from baseline in biomarkers and and immunity related to stress at week 2 and week 4(baseline, week 2, week 4)