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临床试验/NCT03546270
NCT03546270已完成不适用

The Effects of Swimming Training on Arterial Function, Strength and Cardiorespiratory Capacity in Elderly Women With Stage 2 Hypertension

Pusan National University0 个研究点目标入组 100 人开始时间: 2017年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
100
主要终点
Arterial Stiffness

研究概览

简要总结

Aging is associated with progressive decreases in arterial health and function as well as overall fitness. It is crucial to prevent or reduce the negative effects of aging on the vasculature and fitness components by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a swimming (SWM) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx), muscle strength and aerobic capacity in elderly women with stage 2 hypertension.

详细描述

Using a parallel experimental design, participants were randomly assigned to either SWM (n=52) or non-exercising control group (n=48) for 20 weeks. Participant in the SWM group trained 3-4 days/week, progressing in duration from 25 to 45 min. Participants' carotid to radial PWV (crPWV), systolic and diastolic BP, AIx, strength and VO2max were measured at baseline and after 20 weeks of their assigned intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
65 Years 至 85 Years(Older Adult)
性别
Female
接受健康志愿者
否

入选标准

  • •systolic/diastolic BP: 140-179 over 90-119 mm Hg
  • •had experienced the absence of menstruation for at least 1 year
  • •body mass index <30 kg/m2
  • •<1 h of regular exercise per week in the previous year

排除标准

  • •Taking any medications or hormone therapy in previous year

研究组 & 干预措施

Swimming

Experimental

Participants performed SWM training (combination of free style, breast stroke, and backstroke) for 20 weeks. For the first 5 weeks subjects swam 25-30 minutes/day, 3-4 days/week at ~60% of maximal heart rate. As their overall level of fitness and exercise skill improved, the intensity and duration of exercise increased to 40-45 minutes/day, 3-4 days/week at an intensity of 70-75% of the HRmax. Target HR was adjusted based on the observation that maximal heart rate during SWM is approximately 12 beats/min lower than that during running. Each subject was instructed to swim continuously except during the time needed for checking a target heart rate

干预措施: Swimming (Behavioral)

Control

No Intervention

Participants in the non-exercising control group did not participate in a supervised exercise program and visited the laboratory at the same frequency as participants in the swim intervention and underwent recreational activities such as board games

结局指标

主要结局

Arterial Stiffness

时间窗: 20-weeks

via Pulse Wave Velocity

次要结局

  • Pressure Wave Reflection(20-weeks)
  • Cardiorespiratory Endurance (Volume of Maximal Oxygen Consumption)(20-weeks)
  • Diastolic Blood Pressure(20 weeks)
  • Systolic Blood Pressure(20-weeks)
  • Muscular Strength(20-weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Won-mok son

Principal Investigator

Pusan National University

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