Wroclaw Out-Of-Hospital Cardiac Arrest Registry
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- mortality
研究概览
简要总结
The purpose of this study is to assess the efficacy of institutionalized care program of patients with out-of-hospital cardiac arrest.
详细描述
Patients with out-of-hospital cardiac arrest included in the program will be treated with extracorporeal membrane oxygenation (ECMO) assisted cardiopulmonary resuscitation (CPR) with additional invasive procedures including coronary/pulmonary angiography and intervention. This type of treatment was not provided in institutionalized fashion in Wroclaw, Poland. Implementation of this program should improve survival in out-of-hospital cardiac arrest patients, which currently is less than 10%.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age < 60 years
- •witnessed sudden cardiac arrest with immediate CPR
- •supposed cardiac cause of the event
- •ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) at first medical contact with 3 unsuccessful defibrillations (no ROSC)
- •CPR conducted with Lund University Cardiopulmonary Assist System (LUCAS™)
- •Estimated transfer time from the scene to the Emergency Department < 30 minutes.
- •End tidal carbon dioxide (ETCO2) > 10 mmHg
排除标准
- •Total presumed time from 112 call to ECMO implantation longer than 60 minutes
- •Age < 18 years old or > 60 years old;
- •Non-shockable initial rhythm
- •Unavailability of the automated CPR device
- •Unavailability of the catheterisation laboratory
- •Severe concomitant illness with decreased life expectancy
- •Severe body injury
- •Severe active bleeding
- •Terminal cancer
结局指标
主要结局
mortality
时间窗: 1 month
all cause mortality
次要结局
- degree of disability(3 and 6 months after index event)
研究者
Wiktor Kuliczkowski
Head of the Cardiac Catheterisation Laboratory
Wroclaw Medical University