Sensorimotor Treadmill Training to Improve Gait and Balance in Parkinson's Disease
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- Change from Baseline Gait Speed
研究概览
简要总结
Persons with Morbus Parkinson commonly develop gait and balance disorders leading to dependence, loss of mobility and a high risk of falling.
This study investigates the effectiveness of a sensorimotor treadmill intervention to improve walking and balance abilities in persons with early stages of Parkinson's disease. The sensorimotor treadmill training is conducted on a special treadmill device which is challenging the participants by small oscillations. This intervention, which is supposed to simulate walking on natural, uneven surfaces, is compared to a conventional treadmill training.
Hypothesis: Sensorimotor treadmill training leads to larger improvements in walking and balance abilities as compared to conventional treadmill exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Parkinson's disease stage 1-3 Hoehn and Yahr
- •United Parkinson Disease Rating Scale (UPDRS) 'gait' or 'postural stability' subscore of 1 or more
- •Ability to stand unaided and walk without an assistive device
- •Stable medication during the study period
排除标准
- •On-off and wearing-off phenomena
- •Unstable medical or psychiatric illness
- •Clinically relevant cardiovascular or orthopaedic disease
- •Severe polyneuropathy
- •Cognitive impairment
结局指标
主要结局
Change from Baseline Gait Speed
时间窗: 8 weeks and 20 weeks
Self selected walking speed is assessed on a 10 meter walk distance
Change from Baseline Balance
时间窗: 8 weeks and 20 weeks
Mini - Balance Evaluation Systems Test (Mini - BESTest), Postural Sway in the Romberg Test with eyes open and eyes closed for 30 seconds
次要结局
- Change from Baseline Unified Parkinson's Disease Rating Scale (UPDRS)(8 weeks and 20 weeks)
- Change from Baseline Gait Performance(8 weeks and 20 weeks)
- Change from Baseline Mobility(8 weeks and 20 weeks)
研究者
Prof. Dr. Klaus Pfeifer
Prof. Dr.
University of Erlangen-Nürnberg