NL-OMON22174尚未招募不适用
Infusion of ex vivo-cultured allogeneic NK cels in acute myeloid leukemia patients not eligible for stem cell transplantation (a phase I dose escalation study).
Radboud University Nijmegen Medical Centre0 个研究点目标入组 15 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 15
研究概览
简要总结
Spanholtz J, Tordoir M, Eissens D, Preijers F, van der Meer A, Joosten I, Schaap N, de Witte T, Dolstra H. High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy. PLoS One. 2010;5(2):e9221.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. AML patients > 65 year of age;
- •2. Absence of a HLA-Cw ligand for an inhibitory KIR (i.e. homozygous Cw group 1 or 2);
排除标准
- •1. Patients candidates for SCT;
- •2. Progressive disease, no change or only minor response following induction and consolidation therapy;
研究者
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