Effects of Interactive Stepping Exercise on Balance and Cognitive Function in Individuals With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- One-leg stance test
研究概览
简要总结
The objective of this study is to investigate the effects of interactive stepping exercise on balance and cognitive function in individuals with PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Idiopathic PD
- •Hoehn & Yahr stage between 1 to 3
- •Age between 50 to 85
- •Stable pharmacologic treatment for the last 2 weeks
- •Ability to walk 10 meters unassisted or with assistive devices
排除标准
- •Other neurological disorders diagnosis than PD
- •Receiving any neurological surgeries
- •Any musculoskeletal disorder or cardiopulmonary disease that may influence participation in the study
- •The Mini-Mental State Examination (MMSE) < 24 scores
- •Participated in other exercise intervention of study in the past 3 months
- •Colorblindness or color vision deficiency
结局指标
主要结局
One-leg stance test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate static balance ability
Timed up and go test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate functional walking ability
Mini-Balance Evaluation Systems Test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate balance ability
Montreal Cognitive Assessment Chinese version
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate global cognitive function
Digit span test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate executive function
Romberg test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate static balance ability
Sharpened Romberg test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate static balance ability
Stroop color and word test Chinese version
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate executive function
Trail-making test Chinese version
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate executive function
Spatial span test
时间窗: Change from baseline at 8 weeks and 12 weeks
To evaluate visuospatial ability
次要结局
- 10-meter walk test(Change from baseline at 8 weeks and 12 weeks)
- Parkinson's Disease Questionnaire 39(Change from baseline at 8 weeks and 12 weeks)
研究者
Yea-Ru Yang
Professor
National Yang Ming Chiao Tung University