ISRCTN84346215进行中（未招募）2 期
ucleos(t)ide withdrawal in HBeAg negative hepatitis B virus infection to promote HBsAg clearance (NUC-B)
适应症
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 入组人数
- 240
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged 18 years and over
- •2. Chronic HBV infection
- •3. HBeAg negative
- •4. Nucleos(t)ide analogues treatment for =3 years
- •5. HBV DNA < 400 IU/ml =2 years
- •6. Informed consent
排除标准
- •1. Cirrhosis at any time
- •2. HBeAg to anti-HBe seroconversion within the last 3 years
- •3. Interferon use in the last 3 years
- •4. Contraindications to interferon use
- •5. Participation in HBV-specific therapeutic vaccine studies within 12 months
- •6. HCV, HDV or HIV co-infection
- •7. Immunosuppressant use
- •8. Clinically significant comorbidities that, in the opinion of the investigator, render the patient unsuitable
研究者
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