ISRCTN15088122已完成未知
Tranexamic acid for the treatment of significant traumatic brain injury: an international randomised, double blind placebo controlled trial
ondon School of Hygiene and Tropical Medicine (UK)0 个研究点目标入组 12,737 人开始时间: 2011年7月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 12,737
研究概览
简要总结
2012 protocol in http://www.ncbi.nlm.nih.gov/pubmed/22721545 2019 results in https://www.ncbi.nlm.nih.gov/pubmed/31623894 (added 21/10/2019) 2020 sub-study results in https://pubmed.ncbi.nlm.nih.gov/33262252/ (added 07/12/2020) 2021 results in https://pubmed.ncbi.nlm.nih.gov/33928903/ (added 05/05/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •2. Traumatic brain injury
- •3. Within 8 hours of injury (Added 22/01/18: limited to within 3 hours from September 2016)
- •4. Any intracranial bleeding on CT scan OR a GCS of 12 or less
- •5. No significant extra-cranial haemorrhage
- •6. Where the responsible clinician is substantially uncertain as to the appropriateness of antifibrinolytic agents in the patient
排除标准
- •The fundamental eligibility criterion is the responsible clinician's 'uncertainty' as to whether or not to use an antifibrinolytic agent in a particular patient with traumatic brain injury
研究者
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