Osteopathy and Latent Hypothyroidism: Effectiveness of Osteopathic Treatment on TSH in Patients With Latent Hypothyroidism
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 主要终点
- Change in TSH Concentration
研究概览
简要总结
This study evaluates the effectiveness of stimulating the neurological segments c8-th5 in patients with latent hypothyroidism.
One half of the participants will receive an osteopathic manuel treatment in order to stimulate the relevant segments, the other half will receive no treatment.
详细描述
Patients with latent hypothyroidism show an increased hormone status in TSH and a normal hormone status in fT4. A study has shown that osteopathic treatment had positive effects to some symptoms in patients with latent hypothyroidism. The study was using the pain inventory as the instrument to measure the effect. In this study we want to evaluate the effectiveness of the treatment on the hormone status (TSH, fT4) The intervention group will receive a neurological osteopathic stimulation over 5 weeks. A parallel control group will not receive any therapy.
A follow up blood screening (TSH, fT4) will be done. The results of both groups will be compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •latent hypothyroidism
排除标准
- •Factors that Alter Thyroxine and Triiodothyronine Binding in Serum
- •Increased thyroxin-binding globulin
- •Decreased thyroxin-binding globulin
- •Binding inhibitors
- •Inherited Salicylates
- •Pregnancy
- •Androgens
- •Furosemide
- •Neonatal state
- •Anabolic steroids
- •Free fatty acids
- •Estrogens
- •Glucocorticoids
- •Phenytoin
- •Hepatitis
- •Severe illness
- •Carbamazepine
- •Porphyria
- •Hepatic failure
- •nonsteroidal antiinflammatory drug (variable, transient)
- •Nephrosis
- •Methadone
- •Nicotinic acid
- •Mitotane L-Asparaginase
- •5-Fluorouracil
- •SERMS (e.g., tamoxifen, raloxifene)
- •Perphenazine
- •spinal pathologies
结局指标
主要结局
Change in TSH Concentration
时间窗: 5 weeks
次要结局
未报告次要终点
研究者
Emanuel Amier Diekmann
DO
Diekmann, Emanuel Amier