iBAILA - Investigating Brains & Activity to Improve Latino Aging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 主要终点
- Community Healthy Activities Model Program for Seniors (CHAMPS) Physical Activity Questionnaire for Older Adults
研究概览
简要总结
Examine the impact of the BAILAMOS (TM) dance program on lifestyle physical activity
详细描述
Examine the impact of the BAILAMOS (TM) dance program on lifestyle physical activity (PA). Hypothesis 1: Intervention group will demonstrate greater improvement in Lifestyle PA than controls. 2) Test the impact of BAILAMOS (TM) on cognitive function and quality of life. Hypothesis 2: Intervention group will demonstrate greater improvement in cognitive function and quality of life than controls. 3) Test the impact of BAILAMOS (TM) on brain network functional connectivity. Hypothesis 3: Intervention group will demonstrate enhanced Default Mode Network (DMN), Executive Network (EN), and sensorimotor network connectivity vis a vis controls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age > 60 years;
- •Latino/Hispanic;
- •ability to speak Spanish;
- •participation in <150 minutes/week of aerobic exercise;
- •adequate cognitive status as assessed by the Mini Mental State Examination (>14/21);
- •danced < 2 times/month over the past 12 months;
- •willingness to be randomly assigned to treatment or control group;
- •no plans to leave the U.S. > two weeks during the study.
排除标准
- •uncontrolled cardiovascular disease or diabetes mellitus;
- •pacemaker or metallic implants (infusion pumps, metal prostheses, metallic-backed transdermal patches or metallic shrapnel); - claustrophobia that precludes MRI;
- •stroke within the past year;
- •healing or unhealed fracture(s);
- •hip or knee replacement within the past 6 months;
- •heart failure;
- •recurrent falls within the past year;
- •regular use of a walker or wheelchair;
- •weigh more than 300 pounds, as unable to fit into MRI. The EASY (Resnick et al., 2008) will be used to learn if physician consent is needed for program enrollment.
结局指标
主要结局
Community Healthy Activities Model Program for Seniors (CHAMPS) Physical Activity Questionnaire for Older Adults
时间窗: Baseline and 4 months (follow up) .The 4-month post-intervention follow-up assesses average physical activity over the past 4 weeks.
Report minutes of moderate to vigorous level physical activity per week. Weekly frequency and duration of physical activity is used to calculate minutes of moderate to vigorous level physical activity (MVPA) per week.
Activity Counts Per Minute (CPM).
时间窗: Baseline and 4 months (follow up)
Measured through a wrist-worn accelerometer (ActiGraph Model GT3X) worn for 7 days.
次要结局
- Cerebral White Matter Volume - Global(Baseline)
- Verbal Fluency Test - Animals(Baseline and 4 months (follow up))
- Logical Memory I (Immediate) Test(Baseline and 4 months (follow up))
- Cerebral White Matter Volume - Occipital(Baseline)
- Cerebral White Matter Volume - Posterior Cingulate(Baseline and 4 months (follow up))
- Stroop C (Color)(Baseline and 4 months (follow up))
- Logical Memory II (Delayed) Test(Baseline and 4 months (follow up))
- Symbol Digit Modalities Test(Baseline and 4 months (follow up))
- Digit Span Test - Forward(Baseline and 4 months (follow up))
- Digit Ordering Test(Baseline and 4 months (follow up))
- Cerebral White Matter Volume - Frontal(Baseline)
- Cerebral White Matter Volume - Isthmus of the Cingulate(Baseline)
- Cerebral Functional Connectivity - Frontoparietal Network(Baseline and 4 months (follow up))
- Cerebral Functional Connectivity - Salience Network(Baseline and 4 months (follow up))
- Trail Making Test (TMT) Part B(Baseline and 4 months (follow up))
- Verbal Fluency Test - Fruits and Vegetables(Baseline and 4 months (follow up))
- Trail Making Test (TMT) Part A(Baseline and 4 months (follow up))
- Stroop C-W (Color-word Test) of the Stroop Neuropsychological Screening Test(Baseline and 4 months (follow up))
- Cerebral White Matter Volume - Anterior Cingulate(Baseline)
- Cerebral Functional Connectivity - Language Network(Baseline and 4 months (follow up))
- Cerebral White Matter Volume - Temporal(Baseline)
- Cerebral White Matter Volume - Parietal(Baseline)
- Cerebral White Matter Hyper-intensities(Baseline)
- Cerebral Functional Connectivity - Default Mode Network(Baseline and 4 months (follow up))
- Digit Span Test - Backward(Baseline and 4 months (follow up))
研究者
David Xavier Marquez
Professor
University of Illinois at Chicago