A comparative study on the efficacy of Dexmedatomidine and Fentanyl as a local anaesthetic adjuvant to Levobupivacaine 0.125% in epidural labour analgesia- A randomized controlled study

A Comparative study on the efficacy of Dexmedetomidine and Fentanyl as a local anesthetic adjuvant to Levobupivacaine 0.125% in epidural labor analgesia : Randomized controlled study in a tertiary care hospital kancheepuram district

PRIMARY OBJECTIVE

To compare the analgesic effects  of two drugs in epidural anesthesia in antenatal mother

SECONDARY OBJECTIVE

To compare the variables like,

Heart rate, Mean blood pressure, and Spo2

Adverse reactions of parturient women

DATA COLLECTION PROCESS:

Pre anesthetic checkup will be done and those patients who fit into the inclusion criteria will be taken up for the study. Study will be started after ethical committee and institutional committee approval . CTRI registration will be done before enrolling patient to the study.

• NPO of 6 hours for solid foods and 4 hours for liquids (prior to the procedure) will be ensured in all the patients. They would be pre medicated in the night before surgery followed by Inj. Pantoprazole 40 mg IV on the morning of surgery. IV access with 18G venflon secured in all patients. Monitors- Pulse oximeter, NIBP, ECG. ETCO2, Baseline values will be noted.

• Patients will be randomized into two groups 1 and 2 by the computer-generated technique.

• Group 1 includes 12 ml of 0.125% levobupivacaine with 0.5mcg/kg dexmedetomidine

• Group 2 includes 12 ml of 0.125% levobupivacaine with 2mcg/ml fentanyl

• Patients will be monitored for the following

• Blood pressure and heart rate will be monitored noninvasively.

• Intra and postoperative complications if any will be noted.