umbar transforaminal epidural injection versus systemic corticosteroids for the treatment of acute sciatica: a randomized clinical trial

Federal University of Sao Paulo0 个研究点目标入组 100 人开始时间: 2021年3月24日最近更新: 2021年4月12日

适应症

试验速览

暂无简介。

•1. Age over 18 years and who accepted to participate in the research by signing the Informed Consent Form
•2. Symptoms suggestive of acute sciatica such as low back pain radiating to the lower limbs respecting the specific limits of the lumbar dermatomes and physical examination showing signs of root irration to the tensioning maneuvers
•3. Minimum duration of symptoms greater than 72 hours
•4. Maximum duration of symptoms less than 4 weeks
•5. Oswestry Disability Index with a score greater than 30 points
•6. Imaging exams (radiographs and magnetic resonance) compatible with the clinical picture presented by the patients

•1. Refusal to sign the Informed Consent Form (ICF)
•2. Patients who do not use medications and follow the guidelines of the research team
•3. Patients with a clinical condition that requires immediate surgical intervention (for example, cauda equina syndrome)
•4. Patients with a previous history of neoplasms or previous trauma (fractures or dislocations) in the spine
•5. Patients with a previous history of spinal surgery
•6. Patients with comorbidities that indicate chronic use of corticosteroids (autoimmune diseases, conditions of atopy) or that contraindicate the use of this medication class at any time (for example, type 2 diabetes mellitus, uncontrolled systemic arterial hypertension in the last month, pregnancy/puerperium, active peptic ulcer)
•7. Previous history of allergy or intolerance to analgesics with local action and/or iodinated components used in TFEI

发起方

Federal University of Sao Paulo