(Feasibility) Open label Randomised Controlled Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis - HO2T or NO2T Trial

Plymouth Hospitals NHS Trust0 个研究点目标入组 50 人开始时间: 2015年7月13日最近更新: 2019年6月30日

适应症

试验速览

暂无简介。

•Inclusion Criteria
•Adult patients aged 18 years or above.
•Diagnosed with presumed ‘Sepsis’
•Arrive at Derriford Emergency Department by ambulance.
•Provision of informed consent.
•Willing to allow their General Practitioner and consultant, if appropriate,to be notified of participation in the study.
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 100
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 100

•Exclusion Criteria
•The participant may not enter the study if ANY of the following apply:
•Female participants who are pregnant
•Existing diagnosis of chronic obstructive pulmonary disease (COPD)
•A primary diagnosis (or suspected diagnosis) of:
•oan acute cerebral vascular event
•oacute coronary syndrome
•oacute pulmonary oedema
•ostatus asthmaticus
•omajor cardiac arrhythmia (as part of primary diagnosis)
•odrug overdose
•oinjury from burn or trauma
•Participants who require immediate intubation and ventilation on arrival in the Emergency Department
•Participants undergoing or have undergone cardiopulmonary resuscitation in the pre-hospital phase of their treatment.
•Current participation in another Clinical Trial of an Investigational Medicinal Product (CTIMP).

发起方