The BrainHealth Project, a Longitudinal Study in Generally Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100,000
- 试验地点
- 2
- 主要终点
- BrainHealth Index Score
研究概览
简要总结
The BrainHealth Project is a longitudinal study designed to identify factors associated with brain health and cognitive performance across the lifespan. Participants complete online assessments approximately twice per year to measure changes in cognitive, behavioral, and lifestyle-related domains.
Between assessments, participants have access to digital training modules, educational resources, and optional coaching sessions. A subset of participants may be invited to participate in additional components, including neuroimaging.
For an overview of the study and link TO REGISTER please go to -- https://brainhealth.utdallas.edu/programs/the-brainhealth-project/
详细描述
Description of Study:
The BrainHealth Project is a longitudinal study designed to examine factors associated with brain health, including both maintenance and changes in cognitive function across the lifespan. Additionally, researchers aim to identify more personalized practices for promoting brain health.
The study design is informed by prior longitudinal research, namely the Framingham study, demonstrating the value of large-scale, repeated assessments in identifying modifiable factors associated with health outcomes. The goal of this study is to characterize determinants of brain health and support future research on prevention and intervention strategies.
Participants complete online assessments approximately twice per year to measure changes in cognitive performance and related domains over time. Between assessment time points, participants may engage in digital training modules, educational resources, and optional coaching sessions.
Assessments:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 110 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •English-speaking
- •Access to an internet connect and device
- •Able to read information and hear sounds
排除标准
- •Diagnosed neurodegenerative disease
- •History of stroke, concussion, or brain injury that currently hinders you from functioning at your prior level
- •Diagnosed with Autism Spectrum Disorder and not functioning independently
- •For an overview of the study and LINK TO REGISTER please go to -- https://brainhealth.utdallas.edu/programs/the-brainhealth-project/
结局指标
主要结局
BrainHealth Index Score
时间窗: Every 6 months for 10 years
We will assess change on a holistic measure of cognitive, social, well-being, and daily life health on the BrainHealth Index (BHI) across multiple timepoints. Higher score = Better outcome)
Functional Magnetic Resonance Imaging (fMRI) Measure of Neural Correlations
时间窗: Every 6 months for 10 years
We will assess change in regional cerebral brain blood flow (using fMRI) in correlation with gains in complex abstraction across multiple timepoints. (higher correlation = better outcome)
次要结局
未报告次要终点
研究者
Sandra Chapman, PhD
Professor
The University of Texas at Dallas