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临床试验/NCT02551601
NCT02551601终止不适用

Subfoveal Choroidal Thickness in Thai Population

Khon Kaen University1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2015年8月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
150
试验地点
1
主要终点
subfoveal choroidal thickness

研究概览

简要总结

The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using spectral-domain optical coherence tomography with enhanced depth imaging technique.

详细描述

Alteration of choroidal blood supply causes changes in choroidal thickness and results in choroidal abnormalities. These are usually associated with retinal diseases and leading to severe visual dysfunction. Choroidal thickness is therefore helpful in diagnosis and treatment for many chorioretinal conditions. With the advent of spectral domain optical coherence tomography and enhanced depth imaging technique, choroidal thickness has been investigated widely in normal eyes and various chorioretinal diseases including central serous chorioretinopathy (CSC), age-related macular degeneration (AMD), highly myopia and Vogt Koyanagi-Harada disease. Similar to retinal thickness, a normal baseline choroidal thickness might be used for interpretation. This value might be affected by several variables including age, gender and ethnicity. Although there were previous studies on subfoveal choroidal thickness in normal eyes from many countries, there has been no such study in Thailand. The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using SD-OCT and EDI technique.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18 years or above
  • Healthy subjects
  • No ocular diseases
  • Written informed consent form

排除标准

  • patients with systemic diseases that may affect retinal or choroidal thickness including diabetes
  • patients with history of refractive surgeries, intraocular surgeries or retinal laser treatments
  • patients with history of macular, retinal, or optic nerve abnormalities

结局指标

主要结局

subfoveal choroidal thickness

时间窗: up to 4 months

Thickness of choroid at the foveal area

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yosanan Yospaiboon

Department of Ophthalmology, Faculty of Medicine, Khon Kaen University

Khon Kaen University

研究点 (1)

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