Robustness Check of Placement and Measurement Algorithms for Blood Flow Measurement on Common Carotid Artery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 67
- 试验地点
- 1
- 主要终点
- Robustness of placement and measurement algorithms.
研究概览
简要总结
This study is set up to test the robustness of algorithms and models and to optimize them. Furthermore, data are used to investigate the influence of probe orientation on parameters of the common carotid artery.
详细描述
This study has four objectives:
- Determine the robustness of the placement and measurement algorithms with ultrasound images, obtained with different ultrasound system settings and probe movements.
- Verificate and optimize the arterial blood flow model.
- Determine the variation in location and size of the arteries and veins in the area around the common carotid artery.
- Determine the influence of probe orientation on parameters obtained from ultrasound measurements of the common carotid artery.
Sample size and missing data Due to limited time in the operating room, the measurement protocol is divided into four parts. Per protocol part data of 25 patients is deemed sufficient to be able to answer the above-mentioned objectives, which would result in a total of 100 inclusions. However, the investigators expect to perform more than one measurement protocol per patient, due to which a total of 75 inclusions is needed. Patients of whom the data is qualitatively too low to be used for analysis will be replaced. As such, the investigators make sure to have qualitatively good data of 25 patients per protocol part.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult (>18 years) patients.
- •Participant should be able to provide informed consent in Dutch.
排除标准
- •Participant has a known stenosis of the carotid artery.
- •Patient has open wounds in the measurement area (area in the neck around the carotid artery).
结局指标
主要结局
Robustness of placement and measurement algorithms.
时间窗: During data acquisition, which is pre-surgery.
Using the obtained US images of the common carotid artery, the robustness of our algorithms for placement and measurements will be checked.
Verify and improve the arterial blood flow model.
时间窗: During data acquisition, which is pre-surgery.
Using the obtained US images of the common carotid artery, our arterial blood flow model will be verified and adapted.
Orientation of ultrasound probe.
时间窗: During data acquisition, which is pre-surgery.
Using the obtained US images of the common carotid artery, the influence of probe orientation on carotid artery parameters will be investigated.
次要结局
未报告次要终点
研究者
Esmée de Boer
Doctoral Candidate
Catharina Ziekenhuis Eindhoven