Immune Modulators in Women Undergoing IVF----a Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- To explore the relationship between immune mediators and IVF outcome prospectively in women who receive in vitro fertilization treatment.
研究概览
简要总结
Exploring the immune mediators of early pregnancy prospectively may help to identify new early interventions that will increase the likelihood of success and help women make informed decisions regarding their pregnancies.
详细描述
Sera will be obtained from 500 women undergoing IVF at five time periods: cycle Day 2, post HCG, Day 24, Day 28, and/or Day 35.Aliquots of sera will be tested by commercial ELISA kits for concentrations of immune modulators suggestive to be predictive of IVF outcome, such as cytokines (interleukins, tumor necrosis factor, and interferon), neurotrophins (BDNF), protease inhibitors (HE4) and insulin-like growth factors (IGF-1, IGF-2, IGFBP). The results will be correlated with IVF outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 44 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All fresh transfers
排除标准
- 未提供
结局指标
主要结局
To explore the relationship between immune mediators and IVF outcome prospectively in women who receive in vitro fertilization treatment.
时间窗: 35 days
次要结局
未报告次要终点