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临床试验/NCT04289519
NCT04289519Unknown不适用

Retrospective Study on Endoscopic Findings of Gastritis in Children Attending GIT Endoscopic Unit of Assiut University Children Hospital (AUCH) (15 Years)

Assiut University0 个研究点目标入组 500 人开始时间: 2020年9月30日最近更新:
适应症

试验速览

阶段
不适用
入组人数
500
主要终点
causes of gastritis in children as shown by upper endoscopy

研究概览

简要总结

Gastritis defines any (histologically confirmed) inflammation of the gastric mucosa

详细描述

Gastritis is a very common disease in children. The main presentation of children with gastritis is recurrent abdominal pain and dyspepsia or vomiting. Young children may have hematemesis or melena as presentation. Drug induced or food related gastritis presents usually with acute symptoms but Helicobacter pylori gastritis have mainly recurrent abdominal pain and dyspeptic symptoms. Other presentations include diarrhea, constipation, flatulence, bloating, fatigue, low energy level, weight loss, muscle loss, bad breath etc.

The main causes of gastritis are infections, inflammation and other disorders affect the gastric mucosa in pediatric patients. Helicobacter pylori infection is the most common cause of gastritis in children which is also responsible for the majority of duodenal ulcers.

Acute erosive gastritis is most commonly the result of metabolic stress or drug or corrosive injury.

Other major causes of gastritis include celiac disease, allergic disorders, and Crohn's disease .Medication as NSAIDs, uremia, ischemia, shock, radiation, sepsis, trauma, severe burns and surgery.

Endoscopic pictures in acute gastritis may be in the form of:

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
— 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • All children diagnosed as gastritis by upper endoscopy and bio gastric biopsy

排除标准

  • • All children underwent upper endoscopy during the study period not diagnosed as gastritis

结局指标

主要结局

causes of gastritis in children as shown by upper endoscopy

时间窗: average 1 year

* infections * inflammation * Helicobacter pylori * Acute erosive gastritis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

HM Reyad

principle investigator

Assiut University

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