JPRN-UMIN000008711已完成未知
The influence of oral valproate on propofol metabolism - The influence of oral valproate on propofol metabolism
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Dental Anesthsiology and Special Care Dentistry0 个研究点目标入组 33 人开始时间: 2012年8月18日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 33
研究概览
简要总结
There were no significant differences in the propofol level at 5, 10, 15, and 20 min or the free propofol level at 5 min after the intravenous administration of propofol. However, the minimum BIS was significantly lower and the time until the BIS exceeded 60 was significantly longer in the poly-VPA group. In the multivariate regression analysis, belonging to the poly-VPA group was found to be independently associated with the minimum BIS value and the time until the BIS exceeded 60.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16years-old 至 ot applicable(—)
- 性别
- All
入选标准
- 未提供
排除标准
- •Patients without consent of the study
研究者
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