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临床试验/NCT01537445
NCT01537445Unknown不适用

MR-Evaluation of Renal Function-After-Pancreas-transplantation

Uppsala University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2012年2月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
40
试验地点
1
主要终点
Kidney function

研究概览

简要总结

The purpose of this study is to evaluate the beneficial effect of pancreas transplantation for long term kidney function in patients undergoing single-pancreas transplantation.

详细描述

Renal failure in patients who have performed a pancreas transplantation is a hazard for the outcome for these patients. The beneficial effect of pancreas transplantation for renal function is not clear. It is of major importance to early find patients who develops a decrease in renal function and start treatment early and closely monitor these patients in order to avoid further deteriorating renal function. In order to achieve this, there is a need for a easy, fast and sensitive method to evaluate renal function. In this study the investigators plan to use the non-invasive MR to evaluate changes in renal function.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
15 Years 至 75 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with diabetes mellitus
  • Patients undergoing a pancreas transplantation

排除标准

  • Patients undergoing a pancreas transplantation and a renal transplantation at the same time.

结局指标

主要结局

Kidney function

时间窗: Within 3 years

Improvements in kidney function (GFR) and proteinuria after pancreas transplantation.

次要结局

  • Kidney hemodynamics and oxygenation(Within 3 years)

研究者

发起方
Uppsala University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Per Liss

Associate professor

Uppsala University

研究点 (1)

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