Effects of Adding L-Carnitine With Dexamethasone on Respiratory Distress Syndrome Development in Preterm Infants
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- the mean difference in the Apgar score after birth
研究概览
简要总结
The aim of the present study was to investigate the efficacy of L-carnitine therapy on the occurrence and prognosis of respiratory distress syndrome
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women between 30-37 weeks
- •singleton pregnancy
排除标准
- •congenital malformed fetus
- •Extreme premature
研究组 & 干预措施
study group
women will receive dexamethasone 8 mg intramuscular every 8 hours plus single injection of L-carnitine 1 gm slow intravenous
干预措施: Dexamethasone (Drug)
study group
women will receive dexamethasone 8 mg intramuscular every 8 hours plus single injection of L-carnitine 1 gm slow intravenous
干预措施: L-Carnitine 1G/5mL Injection (Drug)
control group
women will receive dexamethasone 8 mg intramuscular every 8 hours plus single injection of saline 1 gm slow intravenous
干预措施: Dexamethasone (Drug)
结局指标
主要结局
the mean difference in the Apgar score after birth
时间窗: 1 minute
Assessment of fetal general condition
次要结局
未报告次要终点
研究者
Ahmed Mohamed Abbas
Principal investigator
Assiut University