NCT07287579尚未招募不适用
Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in Hair Transplantation in Male Androgenic Alopecia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 主要终点
- • To measure hair density using dermoscopy.
研究概览
简要总结
- To compare the efficacy of platlet rich plasma and Nanofat injection as adjuvant therapies with FUE hair transplantation in improving graft survival rate,
- To measure hair density and thickness postoperatively using dermoscopy or trichoscopy.
- To evaluate patient satisfaction and photographic assessment by blinded evaluators.
- To assess any adverse effects or complications related to each modality
详细描述
- Ideal candidates for hair transplantation typically present with a clear, stable pattern of hair loss, characterized by at least 50% thinning or balding in 1 or more areas. The scalp must be healthy, with donor hair of good quality and quantity. Patients must have realistic expectations and be free of medical conditions that compromise surgical outcomes. The safe donor zone is located in the mid-occipital region between the upper and lower occipital protuberances, typically containing 65 to 85 follicular units/cm²
- Intra-operative injection of PRP is beneficial in giving faster density, reducing the catagen loss of transplanted hair, early recovery of the skin, the faster appearance of new anagen hair in FUE hair transplantation.
- This study compares the effects of PRP and Nano fat as adjuvants in Androgenic alopecia patients undergoing FUE hair transplantation.
- Nanofat contain stem cells supposed to improve the results of FUE hair transplantation , but the question that we hope to answer at the end of our study which one we recommend as an adjuvant therapy PRP or Nano fat?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •1. Male patients with stable androgenic alopecia more than 2 years.
- •Age 20-50 years
- •No recent medical hair loss treatments.
排除标准
- •1. Active scalp infections or scarring alopecia.
- •Systemic diseases affecting wound healing.
- •Platelet disorders or anticoagulant use.
- •Smoking or heavy alcohol intake
结局指标
主要结局
• To measure hair density using dermoscopy.
时间窗: • All patients will be followed up about 6-12 months postoperative.
To measure how many hair follicles in each cubic centimetre
次要结局
未报告次要终点
研究者
Shenoda Gamel Fayez
Assistant lecturer in plastic surgery department, faculty of medicine Sohag University hospital.
Sohag University
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