2023-509431-29-00招募中2 期
Treatment with Risedronate for dilated cardiomyopathy due to Troponin T alteration due to K210 deletion.
Fundacion Para La Formacion E Investigacion Sanitaria De La Region De Murcia1 个研究点 分布在 1 个国家目标入组 5 人开始时间: 2024年8月26日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 5
- 试验地点
- 1
- 主要终点
- Change in LVEF, measured by echocardiography, at 6 months.
研究概览
简要总结
To study whether the administration of Risedronate 10 mg/day in patients with dilated cardiomyopathy due to K210 deletion mutation in the Troponin T gene is associated with: A change in left ventricular function, measured by Echocardiogram
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 接受健康志愿者
- 否
入选标准
- •Older than 18 years old
- •Dilated cardiomyopathy due to K210 deletion mutation in the Troponin T gene
- •Patients who have given written informed consent
排除标准
- •Hypersensitivity to Risedronate
- •Hypocalcemia
- •Severe renal failure (eGFR < 30 ml/min/1.73m2)
- •History of esophageal disorders, with delay in transit or esophageal emptying, due to example, stenosis or achalasia
- •Barrett's esophagus
- •Inability to remain upright for at least 30 minutes after taking of the tablet.
- •Active treatment with corticosteroids or chemotherapy
- •Pregnant or breastfeeding women
- •Use of other investigational drugs at the time of inclusion, or during the 30 days prior to inclusion
结局指标
主要结局
Change in LVEF, measured by echocardiography, at 6 months.
Change in LVEF, measured by echocardiography, at 6 months.
次要结局
- Improvement in functional capacity, measured in the stress test with oxygen consumption, at 6 months.
研究者
María Muñoz García
Scientific
Fundacion Para La Formacion E Investigacion Sanitaria De La Region De Murcia
研究点 (1)
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