PREHAB-PEER - A personalized multimodal prehabilitation program including peer counselling by patient support group representatives versus standard perioperative care in colorectal cancer surgery – the multicenter randomized controlled trial - PREHAB-PEER

Universitätsklinikum Heidelberg0 个研究点目标入组 392 人开始时间: 2026年8月31日最近更新: 2026年8月3日

适应症

试验速览

暂无简介。

•Patients (18 years or older) will be included in the trial if they meet all the following criteria:
•i) undergoing elective curatively intended surgery for colorectal cancer (colon and rectum) including resection of hepatic metastasis via atypical or anatomical minor liver re-section in the same operation
•ii) undergoing upfront surgical resection or resection following neoadjuvant chemo(radio-)therapy
•iii) in physical and cognitive condition to adequately conduct all components of the prehabilitation intervention
•iv) able to understand character and individual consequences of the clinical trial and to give written informed consent.
•In addition, at least one of the following validated criteria to be classified as “high-risk” must be fulfilled:
•i) Clinical frailty Scale (CFS) = 3,
•ii) Nutritional Risk Screening (NRS) 2002 = 3
•iii) Age = 65 years
•iv) American Society of Anaesthesiologists (ASA) score = 3.

•Patients with
•i) distant metastases (except for liver metastases with possible curatively intended resection via atypical or anatomical minor liver resection)
•ii) not colorectal-carcinoma as indication for colorectal surgery,
•iii) physical or psychological impairment (e. g. paralysis, mobility problems, delirium, major psychiatric disorders, etc.) that prevents participation in the prehabilitation program
•iv) ASA score >3
•v) inability to postpone surgical resection for 3 weeks e. g. due to clinical indications such as signs of bowel obstruction
•vi) participation in another interventional trial with possible interference with the intervention or outcome of this trial
•vii) expected lack of compliance or language problems
•will be excluded.

发起方