Efficacy of peri operative hydrocortisone and indomethacin treatment in reducing major complications after Whippleâ??s Pancreaticoduodenectomy in high risk patients, R.C.T.

ASIAN INSTITUTE OF GASTROENTEROLOGY0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•All patients undergoing Whippleâ??s PD in Asian Institute of Gastroenterology, Hyderabad
•Patients having >40% acini at cut surface of pancreas ( previous studies have shown that those patients in whom pancreas contain more number of acini are tend to have softer pancreas, more local inflammatory response and hence more chances of Anastomotic leak. Only those patients who are at high risk for leak i.e. more than 40% acini in cut surface of pancreas will be included in the study and recieve the remaining doses of drugs and followed up).

•On table - inoperable patients
•Patients already on steroid treatment
•Patients already on long term NSAIDs treatment
•Patients with Chronic pancreatitis (these patients are at low risk of leak due to hard texture of pancreas, hence will be excluded from the study)
•Patients of Chronic kidney disease
•Patients who suffered stroke or acute coronary syndrome in past
•Known case of peptic ulcer disease
•Patients having thrombocytopenia
•Patients not giving consent for participation

发起方

ASIAN INSTITUTE OF GASTROENTEROLOGY