A Comparative Study of Melatonin and Gabapentin as Premedication for Patients Undergoing Surgery Following Trauma
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- preoperative anxiety
研究概览
简要总结
This project aims to compare the effect of preoperative administration of melatonin and gabapentin in reducing preoperative anxiety, stress markers and postoperative pain levels in trauma patients undergoing surgery. Gabapentin has analgesic as well as sedative properties. Melatonin, a hormone has been extensively used in intensive care units and has found to improve the sleep cycle and reduce pain. It is now being explored as a preoperative medication.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Melatonin
干预措施: Melatonin 6 MG (Drug)
Gabapentin
干预措施: Gabapentin (Drug)
结局指标
主要结局
preoperative anxiety
时间窗: 30 minutes after drug administration
evaluate the difference in the preoperative anxiety score(Numerical Rating Scale ) before and after drug administration
次要结局
- post operative analgesia(24 hours postoperative)
- inflammatory markers(before and 30 minutes after drug administrartion)
- Sedation score(before and 30 minutes after drug administrartion)
研究者
Kelika Prakash
Assistant Professor
All India Institute of Medical Sciences, New Delhi