ISRCTN10965433已完成未知
Effect of oral probiotic supplement improving skin hydration on adults during 12 weeks of intervention: a triple-blind, randomized, placebo-controlled trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 99
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Consent to participate in the study and willing to comply with the protocol and study restrictions
- •2. Females and males aged 20-65 years at randomization
- •3. Corneometer confirmed dry skin, arbitrary unit value under 45, measured from cheek, neck and anterior forearm. A series of 6 measurements will be taken and the middle 4 values will be used to calculate the mean value, which will be expressed in arbitrary units (a.u.). All 6 values from each location will be recorded.
- •4. Dry skin by self-assessment
- •5. Females of childbearing potential to follow a medically approved contraceptive method
排除标准
- •1. Participation in any other clinical trial within the past 2 months before the randomization or planning to do so during the study
- •2. Unable or unwilling to comply with study procedures
- •3. Allergy or intolerance to any ingredient in the investigational products
- •4. Currently diagnosed with atopic dermatitis (AD)
- •5. Current or planned use of corticosteroids, retinoids or UV-treatment
- •6. Use of systemic steroids or systemic antibiotics in the 6 months before randomization
- •7. Use of topical corticosteroids or antibiotics prescribed by a physician or as OTC products in the 2 months before randomization
- •8. Wounds, scars (including severe acne scars and large burn scars) or tattoos at the skin sites to be examined in this study
- •9. History of any cosmetic medical treatment (such as medical chemical- or laser peelings or injections of Botox). Non-cosmetic treatment is not an exclusion criterion unless at site of measurement.
- •10. History of any cosmetic/beauty treatments (such as photofacial or injections of hyaluronic acid, or collagen) at the sites to be examined in this study in the past one year or intention to receive such during the study
- •11. Exposure to UV light treatment (such as solarium) or extensive sun bathing (i.e. skin has reacted to sun bathing) in the past two months before randomization or intention of such during the study
- •12. Screening hematology, serum and urinary laboratory analyses results that are deemed clinically significantly abnormal by the investigator
- •13. Pregnant or breastfeeding or planning pregnancy during the study
- •14. Otherwise considered unsuitable for the study by the principal investigator
研究者
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