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临床试验/NCT01611103
NCT01611103已完成不适用

Cognitive Effects of Transcranial Direct Current Stimulation in Older Adults

Johns Hopkins University2 个研究点 分布在 1 个国家目标入组 43 人开始时间: 2012年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
43
试验地点
2
主要终点
Cognitive Test Performance

研究概览

简要总结

This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities. In this research, a 9 volt battery is used to deliver very weak electrical current to the surface of the scalp while participants complete cognitive tasks. Our aim is to find out whether tDCS will improve task performance in adults over the age of 55.

详细描述

Participants enrolled into this study may be asked to do the following:

  • Grant permission for the researchers to view medical records associated with their language/cognitive difficulties (if applicable).
  • Complete a questionnaire, provide a health history, and take some pencil-and-paper tests of problem-solving and memory in order to verify eligibility to participate and to able to safely undergo the experimental procedures.
  • Complete several tasks (i.e., saying words out loud, naming objects, drawing designs, remembering lists of words, searching for images or letters, and/or completing puzzles) based upon a number of cognitive functions such as language, memory, vision, processing, and perception.
  • Wear electrodes that will be placed on the scalp with a large rubberized band. These electrodes will administer very weak electrical current (tDCS) from a 9 volt battery for 20 to 60 minutes.
  • Participate in several study conditions. The exact conditions and their order will be randomized. Under some conditions, participants may receive active stimulation (tDCS) and under other conditions, they may receive sham stimulation.
  • The experimental sessions will last approximately 2 hours and participants may be asked to have more than one testing session in a day or to return for additional sessions.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
55 Years 至 79 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Over the age of 55
  • Right Handed
  • Native English speaker

排除标准

  • History of Seizures
  • Any implanted metal device or pacemaker
  • Appreciable deficits in hearing or vision
  • Greater than 1.5 standard deviations below demographically adjusted means on cognitive screen
  • Dementia or Mini Mental Exam below 24

结局指标

主要结局

Cognitive Test Performance

时间窗: The average time frame is 2 hours

Cognitive test performance by subjects will be evaluated upon completion of enrollment to determine if tDCS improved performance on cognitive tests

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Barry Gordon, M.D., Ph.D.

Editor-in-Chief, Cognitive and Behavioral Neurology/Therapeutic Cognitive Neuroscience Professor/Professor of Neurology and Cognitive Science

Johns Hopkins University

研究点 (2)

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