Local Injection of Autologous Platelet Rich Plasma During Repair of Disrupted Surgical Wounds at Obstetrics and Gynecology Department: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Duration of hospital stay
研究概览
简要总结
Patients with disrupted wounds will either managed as usual or managed by Platelet rich plasma local infiltration in the wound edges
详细描述
The patients with disrupted surgical wounds will be cleansed, debrided and closed with infiltration of platelet rich plasma in one group and the other group will be closed without infiltration of Platelet rich plasma
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Patients were not allowed to know allocations
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Disrupted surgical wounds after cesarean sections and other gynecological operations
- •Body mass index 18-25
- •Hemoglobin > 10.5gm/dl
- •Albumin >3.5gm/dl
排除标准
- •Medical disorders asDiabetes mellitus (DM), Liver disease or systemic lupus erythymatosus (SLE)
- •Patient on corticosteriod therapy
- •Thrombocytopenia
- •Coagulation disorders
研究组 & 干预措施
Intervention group
All patients in this group will be manged as usual with infiltration of platelet rich plasma in thee wound edges during closure of the wounds
干预措施: Platelet rich plasma infiltration in the wound edges (Procedure)
Control group
All patients in this group will be managed by repair of wounds without infiltration of platelet rich plasma
干预措施: Closure of wound without platelet rich plasma infiltration (Procedure)
结局指标
主要结局
Duration of hospital stay
时间窗: 30 days
Time during which patient is admitted
Complete wound healing
时间窗: 30 days
time needed for complete wound closure
次要结局
- Failure of complete wound healing(30 days)
- Need fo tertiary suture(30 days)
研究者
Ayman S Dawood, MD
Lecturer
Tanta University