Global, Regional, and National Burdens of Pancreatic Cancer and Pancreatitis Among Older Adults From 1990 to 2021 With Projections to 2040: A Comprehensive and Comparative Investigation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 723,415
- 主要终点
- Incidence
研究概览
简要总结
Using data from the Global Burden of Disease Study 2021, the investigators analyzed age-standardized incidence, mortality, and disability-adjusted life-years (DALYs) for pancreatic cancer and pancreatitis in adults aged ≥70 years across 204 countries and territories, stratified by sex, Socio-Demographic Index (SDI), health system performance, and region. The investigators calculated estimated annual percentage changes (EAPCs), applied age-period-cohort modelling, and used Bayesian models to project future burden. Attributable burdens for key risk factors were also estimated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis with pancreatic cancer or pancreatitis
- •Diagnosis in 1990 through 2021
- •Age 70+ years
排除标准
- •Age <70 years
- •Other non-pancreatic diseases
研究组 & 干预措施
Pancreatic Cancer
干预措施: Natural history (Biological)
Pancreatitis
干预措施: Natural history (Biological)
结局指标
主要结局
Incidence
时间窗: 1990-2021
The number of new cases of a givencause during a given period in aspecified population. It is xpressed as the number of newcases in a year divided by the mid-year population size.
Deaths
时间窗: 1990-2021
Deaths occurring in a population during a certain time period.
Disability-adjusted life years (DALYs)
时间窗: 1990-2021
The sum of years lost due to premature death (YLLs) and yearslived with disability (YLDs). DALYs are also defined as years of healthy life lost.
次要结局
未报告次要终点