Safe Use of CPAP During Preoxygenation and PEEP After Apnoea During Induction of General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Number of breaths until return of CO2.
研究概览
简要总结
The study compares the safety of using pressure controlled ventilation with a positive end-expiratory pressure (PEEP) during induction of general anaesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.
详细描述
Using a continuous positive pressure (CPAP) during preoxygenation, followed by pressure controlled ventilation with PEEP after apnoea during induction of general anesthesia, might offer several benefits but safety issues needs more investigation. This study compares the safety of using pressure controlled with PEEP during induction of general anesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Normal or overweight patients scheduled for day case surgery in general anesthesia.
- •American Society of Anesthesiologists functional class I-III.
- •Body Mass Index 18.5-30.
排除标准
- •Increased risk of regurgitation of gastric content.
- •Symptomatic asthma, COPD or heart failure.
- •Peripheral oxygen saturation (SpO2) breathing air <94 %
- •Anticipated difficult airway.
- •Anatomical features making it difficult to keep a tight seal during maskventilation.
结局指标
主要结局
Number of breaths until return of CO2.
时间窗: 2 minutes
When starting ventilation after apnea the number of breaths given until the return of CO2 is at least 1.3 kPa at a respiratory frequency of 10 per minute.
次要结局
未报告次要终点
研究者
Lennart Edmark
Consultant, Principal Investigator
Region Västmanland