NL-OMON27429尚未招募不适用
A randomized phase III study of erlotinib compared to intercalated erlotinib with cisplatinum pemetrexed as first-line therapy for advanced EGFR mutated non-small-cell lung cancer. The NVALT-17 study
Stichting NVALT studiesLuijbenstraat 155211 BR Den BoschThe Netherlands0 个研究点目标入组 150 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Histologically/cytologically proven stage III or IV NSCLC.
- •Tumor treatment-naive.
- •Documented activating EGFR mutation in exon 18, 19 or exon 21.
- •Measurable disease.
- •Age ≥ 18 years.
- •Males and females.
- •ECOG Performance Status of 0 – 3.
- •Life expectancy > 12 weeks.
- •Adequate contraception for females of childbearing potential.
- •Adequate contraception for male participants.
排除标准
- •Documented brain metastasis.•Concomitant treatment with experimental medicines, potent CYP3A4 inhibitors or inducers.
- •Previous cytotoxic chemotherapy for lung cancer less than 2 years before study entry.
- •For curatively treated lung cancer: (adjuvant) chemotherapy or chemo-radiotherapy less than 12 month prior to the study entry.
- •Pregnancy or lactation.
研究者
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