Repetitive Transcranial Magnetic Stimulation (rTMS) versus sham rTMS in Body Dysmorphic Disorder - rTMS-BDD

Academisch Medisch Centrum0 个研究点目标入组 56 人开始时间: 待定最近更新: 2024年4月9日

适应症

试验速览

暂无简介。

•1. Age 18 to 65 years old;
•2. Diagnosed with Body Dysmorphic Disorder (BDD), based on Body Dysmorphic
•Disorder - Yale Brown Obsessive Compulsive Scale (BDD-YBOCS);
•3. Nonresponse (defined as <50% response on symptoms measured by the BDD-YBOCS)
•after one type of medication treatment, SSRI, maximum dose and adequate
•4. Medication is set 6 weeks prior to the start, and could not be changed
•during the study

•Exclusion criteria
•1. Intracerebral metal implants (e.g. cochlear implant, brain stimulator);
•2. (History of) epilepsy or epilepsy in a first degree relative;
•3. Any other neurological disorder with seizure risk;
•4. Acute suicidal ideations, or any psychological crisis (contact with the
•outpatient crisis service or admission in psychiatric hospital);
•5. Bipolar disorder;
•6. Current disorder in substance abuse (opiate, ketamine, LSD,
•(meth)amphetamine, cocaine, solvents, cannabis, benzodiazepines or barbiturate)
•or alcohol abuse;
•7. Any known other serious somatic health problem;
•8. Pregnancy;
•9. Primarily autism spectrum disorder or primarily personality disorder (using
•SCID-5-P at baseline for personality disorders). Given that this is often seen
•secondarily in BDD patients.
•rTMS Contraindications:
•1. History of epileptic seizures or epilepsy in a first degree relative,
•irregular sleep/ wake rhythm;
•2. Cardiac demand pacemakers;
•3. Implanted defibrillators;
•4. Implanted neurostimulators;
•5. Cochlear implants.

发起方