The Variation in Electrode Configuration for Termination of Out-of-Hospital Rhythms That Are Shockable (VECTORS) Trial: A Pragmatic Trial of Anterior-Posterior Versus Anterior-Lateral Initial Defibrillator Pad Placement for Out-of-Hospital Cardiac Arrest
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 1,500
- 主要终点
- Post-Shock Return of Spontaneous Circulation (ROSC)
研究概览
简要总结
The purpose of this study is to compare the effectiveness of two defibrillator pad placements, one where pads are placed on the front of the chest and back (anterior-posterior [AP]) and one where the pads are placed on the front and side of the chest (anterior-lateral [AL]), for the treatment of cardiac arrest. Both pad placement locations are recommended for use by the American Heart Association (AHA) and International Liaison Committee on Resuscitation (ILCOR) and are used in standard treatment. The investigators are hoping to find out if one pad position is more effective than the other in the treatment of cardiac arrest.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Emergency medical services (EMS)-treated non-traumatic out-of-hospital cardiac arrest
排除标准
- •ROSC at EMS arrival (e.g., bystander AED shock with ROSC prior to EMS care) without rearrest during EMS care
- •Known prisoners
- •Known pregnant patients
- •Known pediatric patients (treated under the pediatric algorithm, generally <15 years)
- •Known preexisting do-not-resuscitate orders limiting care
研究组 & 干预措施
Anterior-Posterior
Defibrillation pads placed initially in the anterior-posterior position.
干预措施: defibrillator electrode pads (Device)
Anterior-Lateral
Defibrillation pads placed initially in the anterior-lateral position.
干预措施: defibrillator electrode pads (Device)
结局指标
主要结局
Post-Shock Return of Spontaneous Circulation (ROSC)
时间窗: day 1
Any palpable pulse documented at any time after the first EMS shock
次要结局
- Time to first rhythm analysis(day 1)
- Time to initial shock(day 1)
- Total EMS shocks(day 1)
- Time to ROSC(day 1)
- Survival to hospital admission(day 1)
- Survival to hospital discharge(through study completion, an average of 7 days)
- Survival to hospital discharge with favorable outcome(through study completion, an average of 7 days)
研究者
Joshua Lupton
Principal Investigator
Oregon Health and Science University