NCT01456754已完成不适用
Effect of Feeding Frequency on Glucose and Insulin Metabolism and Substrate Partitioning in Impaired Glucose Tolerant (IGT) Men
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Insulin metabolism
研究概览
简要总结
The purpose of this study is to determine the effect of feeding frequency on glucose and insulin metabolism and substrate partitioning in impaired glucose tolerant (IGT) men.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •BMI: 20-35 kg/m2
- •Gender: Male
- •Age: subjects has to be older than 18 and younger than 70 years old
- •Impaired Glucose Tolerant (IGT) = plasma glucose, two hours after consuming 75g glucose, appears to be superior to 7.8mmol/l (normal level) but remains inferior to 11.1mmol/l (diabetes level) and fasting plasma glucose is less than 7.0mmol/l.
- •Caucasian
排除标准
- •Lactose intolerant
- •Diabetes Mellitus
- •Cardiovascular diseases
- •Stomach and intestinal diseases
- •Normal glucose levels after 2 hours
- •Anticoagulants
- •Medication that has a effect on energy and glucose homeostasis and absorption of foods
- •Conditions or situations when subjects can't lose 500 ml blood
结局指标
主要结局
Insulin metabolism
时间窗: 24 hour profile
Glucose metabolism
时间窗: 24 hour profile
次要结局
- Metabolic markers (FFA and TG metabolism)(24 hour profile)
- Change in substrate partitioning (fat, carbohydrate and protein oxidation) between the two intervention diets(24 hour profiles)
研究者
研究点 (1)
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