The Effect of Various Serving Sizes of Lentils and Other Starchy Meals on Post Prandial Blood Glucose Response and Insulin
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Postprandial Blood Glucose
研究概览
简要总结
The purpose of this study is to assess the effects of consuming either 1/2 or 1/4 cup servings of lentils on post-prandial blood glucose and insulin as compared to 4 types of starchy foods (corn, macaroni, white potato, white rice).
详细描述
Eligible participants will undergo a total of 6 study visits. During each visit, a fasted blood sample will be taken by fingerprick, and approximately 500 µL of blood will be dripped into a collection tube. The participant will then consume a meal of either: two types of lentils, corn, macaroni, white rice, or white potato. All study days will be randomized. Each meal will be served in either 1/4 or 1/2 cup servings depending on the study block. Six more blood samples will be taken by fingerprick at 15, 30, 45, 60, 90 and 120 minutes after the beginning of the meal.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men and women
- •Age 18-40 years
- •Body mass index (BMI) 20-30 kg/m2
排除标准
- •Tobacco use
- •Pregnant or breastfeeding
- •Fasting blood glucose ≥ 7.0 mmol/L
- •Two hour blood glucose ≥ 11.1 mmol/L after consuming 75g glucose drink (Oral Glucose Tolerance Test beverage)
- •Any major medical condition including a history of AIDS or hepatitis
- •Medical or surgical event requiring hospitalization within 3 months of randomization
- •Any medications except a stable dose (3 months) of oral contraceptives, blood pressure or statin medications
- •Blood pressure >140/90 mm Hg
- •Natural health products (NHPs) used for glycemic control
- •Probiotic supplements
- •Dietary fibre supplements
- •Consumption of >4 servings of pulses per week
- •Food allergy or non-food life threatening allergy
- •Shift workers
- •Alcohol consumption >14 drinks/week or >4 drinks/sitting
- •Recent or intended significant weight loss or gain (>4 kg in previous 3 months)
- •Elite athletes
研究组 & 干预措施
1/4 cup
1/4 cup serving size arm
干预措施: 1/4 cup- Small red lentil (Other)
1/4 cup
1/4 cup serving size arm
干预措施: 1/4 cup- Small green lentil (Other)
1/4 cup
1/4 cup serving size arm
干预措施: 1/4 cup- corn (Other)
1/4 cup
1/4 cup serving size arm
干预措施: 1/4 cup- macaroni (Other)
1/4 cup
1/4 cup serving size arm
干预措施: 1/4 cup- white potato (Other)
1/4 cup
1/4 cup serving size arm
干预措施: 1/4 cup- white rice (Other)
1/2 cup
1/2 cup serving size arm
干预措施: 1/2 cup- white potato (Other)
1/2 cup
1/2 cup serving size arm
干预措施: 1/2 cup- small red lentil (Other)
1/2 cup
1/2 cup serving size arm
干预措施: 1/2 cup- small green lentil (Other)
1/2 cup
1/2 cup serving size arm
干预措施: 1/2 cup- corn (Other)
1/2 cup
1/2 cup serving size arm
干预措施: 1/2 cup- macaroni (Other)
1/2 cup
1/2 cup serving size arm
干预措施: 1/2 cup- white rice (Other)
结局指标
主要结局
Postprandial Blood Glucose
时间窗: 2 hours Postprandial
Postprandial Blood Insulin
时间窗: 2 hours postprandial
次要结局
未报告次要终点
研究者
Alison Duncan
Professor
University of Guelph