NCT03474939已完成4 期
The Effect of Midazolam Premedication on Copeptine Concentration in Blood
Medical University of Warsaw1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2017年4月3日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Change in copeptin concentration
研究概览
简要总结
The study aim is to assess whether premedication with midazolam prior to surgery affects copeptin concentration in blood.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for elective surgery
- •Patients with no chronić illness and considered ASA 1 by anesthesiologist
- •Patients with mild and controlled chronic illness considered ASA 2 by anesthesiologist
排除标准
- •Patient refusal
- •Chronic illness requiring intense treatment or uncontrolled illness (ASA 3 or more)
研究组 & 干预措施
PLACEBO
Placebo Comparator
Patients receive 1000mg Glucose tablets night before and 60 minutes prior to surgery during premedication
干预措施: Placebo Oral Tablet (Other)
MIDAZOLAM
Active Comparator
Patients receive midazolam 7,5mg night before and 60 minutes prior to surgery as part of preanesthetic medication
干预措施: Midazolam Oral Tablet (Drug)
结局指标
主要结局
Change in copeptin concentration
时间窗: 48 hours
Change in the concentration of copeptine measured in blood serum
次要结局
未报告次要终点
研究者
Marek Janiak
Principal Investigator
Medical University of Warsaw
研究点 (1)
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