Prevalence of HbA1C in Different Categories of Obesity in Women With PCOS'A Propective Randomized Control Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Prevalence of HbA1C in both arms of the cohort of subjects
研究概览
简要总结
Women with PCOS have been observed to be potential diabetics.Recently,American Diabetes Association has suggested screening of women with PCOS for HbA1C.
详细描述
In view of recent suggestion of American Diabetes Association(ADA)to screen women with PCOS for HbA1C,we intend to study its prevalence in all categories of obesity in women with PCOS.
Women with PCOS by Rotterdam criteria will be screened for insulin resistance by using different techniques or tests.
Further, the sensitivity and specificity of HbA1C will be compared with sensitivity and specificity of other insulin resistance markers such as OGTT, Free androgen index, free testosterone, fasting insulin to glucose ratio, HOMA-IR and HOMA-B-CELL.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 40 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI of 25-35 Kg/Mt2
- •Atleast three of the Rotterdam criteria for diagnosis of PCOS.
- •Subjects with well stabilized Thyroid,if they had documented evidence of previousthyroid disorder.
排除标准
- •Subjects with documented diagnosis of Metabolic Syndrome.
- •Subjects with laparocopic and histopathologic diagnosis of Endometriosis. 3Subjects with Primary hyperprolectineamia.
- •4.Subjects with basal FSH >/=15mIU/ml. 5.Subjects with continuously elevated 17-0h-p.
结局指标
主要结局
Prevalence of HbA1C in both arms of the cohort of subjects
时间窗: September 2013
HbA1C has been suggested as a potential marker for NIDDM in subjects with PCOS
次要结局
未报告次要终点
研究者
M.R. Bharucha
Faram E.Irani
Southern Cross Fertility Centre