Catheter ablation versus Amiodarone to pRevent Future ventricular tachycardia Episodes in patients with a defibrillator and a history of a myocardial infarction - CARFE 2

Isala klinieken department Cardiology0 个研究点开始时间: 2011年4月27日最近更新: 2012年3月19日

试验速览

暂无简介。

•1.prior myocardial infarction, at least 3 months ago
•2.ICD implantation for any cause except for: Brugada syndrome, ARVC, HCM, LQTS, SQTS, cathecholaminergic polymorphic VT, other channelopathies
•3.ICD therapy (shock or ATP) for VT or VF without a reversible cause
•4.Optimal revascularization before ICD implantation performed
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•1.Age < 18 years
•2.use of amiodarone more than 7 days before randomization within the period of 3 months before randomization
•3.Inability to use amiodarone due to past side effects
•4.Class I antiarrythmic drugs not stopped = 5 times ½T prior to randomization
•5.Protruding LV thrombus or cardiac tumor on pre-ablation echocardiogram
•6.Acute myocardial infarction within the preceding 3 months
•7.non-reversible Class IV NYHA heart failure
•8.Valvular heart disease or mechanical heart valve precluding access to the left ventricle.
•9.Unstable coronary artery syndrome or active myocardial infarction
•10.Cardiac surgery within the past 2 months
•11.mechanical mitral or tricuspid valve prothesis
•12.Serum creatinine > 220 mmol/L (2.5 mg/dL)
•13.Thrombocytopenia or coagulopathy
•14.Contraindication to anticoagulation
•15.stroke within past 30 days
•16.Pregnancy

发起方

Isala klinieken department Cardiology