Biomarkers for Skin barrier and inflammation in Children with Atopic Dermatitis - BioSCAD

Academisch Medisch Centrum0 个研究点目标入组 150 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•100 children with atopic dermatitis, male or female, aged between 0 and 12 years, will be participating in this study.;50 children without any skin disorder or atopy (such as food allergy, allergic rhinoconjunctivitis and allergic asthma), as well as no atopy in first degree relatives, male or female, aged between 0 and 12 years, will be participating as controls

•No clinically skin lesion to obtain tape strips from.
•Use of corticosteroids or other anti-inflammatory topical treatment on the skin lesion(s) selected for tape stripping 1 week prior to the procedure.
•Use of emollients, soap, and cosmetics on the skin lesion(s) selected for tape stripping 48 hours prior to and during the hospital visit day.
•Use of oral antihistamin 1 week prior to the hospital visit day.
•- Onset of atopic dermatitis after the age of 2
•- History of remission of atopic dermatitis without treatment (except emollients) for longer than 1 year ;For controls:
•history of atopy or first degree relative with atopy
•Use of emollients, soap, and cosmetics on the skin lesion(s) selected for tape stripping 48 hours prior to and during the hospital visit day.

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