Incidence of Venous Thrombotic Event After Curative Colon Cancer Surgery in an Enhanced Recovery After Surgery Program
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,141
- 主要终点
- Postoperative venous thromboembolic event
研究概览
简要总结
Based on data on a cohort of 2,141 patients undergoing elective colonic cancer resection in an ERAS program, the incidence of postoperative thromboembolic events is estimated in patients no receiving prolonged thromboembolic prophylaxis.
详细描述
The Copenhagen cOmplete Mesocolic Excision Study (COMES) database contains comprehensive data on preoperative, intraoperative, postoperative and tumor related variable on patients undergoing elective colonic cancer resection at four public university clinics providing all colorectal cancer treatment for the 1.8 million residents of the Capital Region of Denmark during the period 2014-2017.
None of these hospitals had implemented prolonged thromboembolic prophylaxis after discharge.
The medical records were reviewed with focusing on VTE prophylaxis, ongoing preoperative and postoperative anticoagulant treatment, the length of hospital stay (LOS), and readmission to ensure high data validity.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •elective macroradical resection for UICC Stage I-III colonic adenocarcinoma
排除标准
- •concomitant rectum resection
- •soly appendix carcinoma
- •diagnosed with pulmonary embolism or deep venous thrombosis before primary discharge
- •dying before discharge from the hospital or discharged at postoperative day 28 or later
- •treatment with vitamin K antagonists, heparin or new oral anticoagulants before or after surgery
- •VTE less than 3 months before the colon resection
结局指标
主要结局
Postoperative venous thromboembolic event
时间窗: 60 days
Deep venous thrombosis or pulmonary embolism
次要结局
未报告次要终点